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Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

✍ Scribed by Kavon Rezai-Zadeh; Jared Ehrhart; Yun Bai; Paul R Sanberg; Paula Bickford; Jun Tan; R Douglas Shytle


Book ID
119907366
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
344 KB
Volume
5
Category
Article
ISSN
1742-2094

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## Abstract Recent studies have shown that the 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) possess antiinflammatory and immunomodulatory properties, distinct from their action of lowering serum lipid levels. Moreover, results of epidemiological studies suggest that long‐ter