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P1-065: Oxidative load regulates amyloid burden in vitro and in vivo in an APP X PS1 transgenic mouse model of Alzheimer's disease

✍ Scribed by Fahd Choudhry; Paul T. Francis; David R. Howlett; Jill R.C. Richardson; Robert J. Williams


Book ID
118464237
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
59 KB
Volume
4
Category
Article
ISSN
1552-5260

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## Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with senile β‐amyloid (AΞ²) plaques and cognitive decline. Neurogenesis in the adult hippocampus is implicated in regulating learning and memory, and is increased in human postmortem brain of AD patients. Howe