P077 NPM1 and FLT3 mutations in acute myeloid leukemia
โ Scribed by S. Nahajevszky; A. Tordai; A. Szilvasi; N. Meggyesi; E. Adam; A. Kozma; S. Lueff; N. Lovas; B. Kapas; Z. Matrai; A. Sipos; T. Masszi; H. Andrikovics
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 58 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0268-960X
No coin nor oath required. For personal study only.
โฆ Synopsis
Recognition of specific skin manifestations of acute myelogenous leukemia is important because they have prognostic value and always indicates poor prognosis.
P074 Jumping translocation of 1q in a case of childhood acute lymphoblastic leukemia, type L3 with t(8;14
๐ SIMILAR VOLUMES
Mutations affecting NPM, FLT3 ITD and TKD were present in 25% (30/120), 22% (26/120) and 8/120 (7%), respectively. NPM mutations were most prevalent in patients with normal karyotype (24/52; 46%) and were associated with FLT3-ITD mutations (16/26; 62%). Regarding the prognostic significance of NPM a