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P-489 Hypoxia inducible factor-1 alpha in non-small cell lung cancer: Relation to other biological factors and prognosis

✍ Scribed by Swinson, Daniel E.B.; Louise Jones, J.; Cox, Giles; Richardson, Donna; Harris, Adrian; O'Byrne, Kenneth J.


Book ID
118572185
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
182 KB
Volume
41
Category
Article
ISSN
0169-5002

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Hypoxia-inducible factor-1Ξ± in non small
✍ Daniel E.B. Swinson; J. Louise Jones; Giles Cox; Donna Richardson; Adrian L. Har πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 199 KB

## Abstract Hypoxia‐inducible factor (HIF)‐1Ξ± is the regulatory subunit of HIF‐1 that is stabilized under hypoxic conditions. Under different circumstances, HIF‐1Ξ± may promote both tumorigenesis and apoptosis. There is conflicting data on the importance of HIF‐1Ξ± as a prognostic factor. This study