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P-299 Epigenetic inactivation of the candidate tumor suppressor gene SLIT-2 in SCLC and NSCLC lung cancers

✍ Scribed by Morrissey, Catherine; Toyooka, Shinichi; Fong, Kwun; Dallol, Ashraf; Latif, Farida; Gazdar, Adi; Minna, John D.

Book ID: 118571999
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 188 KB
Volume: 41
Category: Article
ISSN: 0169-5002
DOI: 10.1016/s0169-5002(03)92267-7

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## Abstract Allelic imbalance (AI) on chromosome arm 22q has been detected in 20%–40% of colorectal cancers, suggesting that this chromosome arm has a tumor‐suppressor gene involved in colorectal carcinogenesis. Recently, we isolated a candidate tumor‐suppressor gene, __MYO18B__, at 22q12.1, that i