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Deletions in chromosome 4 differentially associated with the development of cervical cancer: evidence of slit2 as a candidate tumor suppressor gene

✍ Scribed by Ratnesh Kumar Singh; Dipanjana Indra; Sraboni Mitra; Ranajit Kumar Mondal; Partha Sarathi Basu; Anup Roy; Susanta Roychowdhury; Chinmay Kumar Panda

Book ID: 106134563
Publisher: Springer
Year: 2007
Tongue: English
Weight: 558 KB
Volume: 122
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-007-0375-6

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## Abstract Loss of heterozygosity (LOH) on the short arm of chromosome 8 occurs at high frequencies in many tumor types, including colorectal carcinoma. We have previously used microcell‐mediated chromosome transfer (MMCT) to map an approximately 7.7 Mb colorectal cancer suppressor region (CRCSR)