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P-278 RASSF1A methylation and k-ras in sputum of patients with lungcarcinoma

โœ Scribed by Thunnissen, F.; Bolijn, A.; Hol, B.; Prinsen, C.


Book ID
118573186
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
146 KB
Volume
49
Category
Article
ISSN
0169-5002

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K-ras mutation appears in about 60% of patients with non-small-cell lung cancer (NSCLC). This freqLency and its presence in normal appearing tissues point to the potential of ras oncogene mutation to serve as a good biomarker. Using enriched PCR (EPCR), which enables the detection of one mutant alle