✦ LIBER ✦

Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers

✍ Scribed by Yang Liu; Weimin Gao; Jill M Siegfried; Joel L Weissfeld; James D Luketich; Phouthone Keohavong

Book ID: 115011144
Publisher: BioMed Central
Year: 2007
Tongue: English
Weight: 335 KB
Volume: 7
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-7-74

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Multiplicity of abnormal promoter methyl

Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers

✍ Kevin K. Divine; Leah C. Pulling; Patricia G. Marron-Terada; Kieu C. Liechty; Te 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 126 KB

## Abstract The prevalence of methylation of the __p16, DAPK__ and __RASSF1A__ genes was investigated in lung adenocarcinoma from smokers, former uranium miners and never smokers. The association between a common genetic alteration in adenocarcinoma, mutation of the __K‐ras__ gene and methylation o

Polymorphisms in DNA repair genes XPD an

Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers

✍ Wei-Min Gao; Marjorie Romkes; Jill M. Siegfried; James D. Luketich; Phouthone Ke 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB

## Abstract The etiology of lung cancer in population with little or no tobacco exposure is not well understood. Individual genetic susceptibility factors have been suggested to contribute to lung cancer risk in this population. Mutations in the p53 tumor suppressor gene are implicated in the devel

Frequencies of p16INK4a promoter hyperme

Frequencies of p16INK4a promoter hypermethylation, p53 and K-ras mutations detectable in exfoliative material differentiate between chronic smokers and lung cancer patients

✍ Kersting, M; Friedl, C; Kraus, A; Behn, M; Kersting, M; Fried, C; Kraus, A; Behn 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 202 KB

Influence of XPD variant alleles on p53

Influence of XPD variant alleles on p53 mutations in lung tumors of nonsmokers and smokers

✍ Sai-Mei Hou; Annamaria Kannio; Sabrina Angelini; Susann Fält; Fredrik Nyberg; Ki 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 48 KB

Aberrant promoter methylation of RASSF1A

Aberrant promoter methylation of RASSF1A, P16, DAPK, and Metallothionein-IA in human lung exposed to metals and cigarette smoke condensate (CSC)

✍ H. Hamed; R. Gherbal; A. Torky; H. Foth 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 81 KB

K-ras oncogene activation in lung adenoc

K-ras oncogene activation in lung adenocarcinomas from former smokers evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung

✍ William H. Westra; Robbert J. C. Slebos; G. Johan A. Offerhaus; Steven N. Goodma 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 782 KB