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Oxygen-dependence of chromosomal aberrations in Fanconi's anaemia

✍ Scribed by Joenje, Hans; Arwert, Fré; Eriksson, Aldur W.; de Koning, Han; Oostra, Anneke B.

Book ID
109722311
Publisher
Nature Publishing Group
Year
1981
Tongue
English
Weight
228 KB
Volume
290
Category
Article
ISSN
0028-0836

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Blood samples from four healthy individuals and from seven Fanconi anaemia (FA) patients were cultured at oxygen tensions ranging from 3% to 45% O2. Cultures were harvested at 72 h and scored for chromosomal aberrations. In the majority of FA patients the aberration frequency showed a tendency to in

Spontaneous and adenovirus type 12-induc
Spontaneous and adenovirus type 12-induced chromosome aberrations in fanconi's anaemia fibroblasts
✍ J. K. McDougall 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 French ⚖ 641 KB

## Abstract The spontaneous aberrations which occur in cells from patients with Fanconi's anaemia have been shown to be distributed in a random manner. Adenovirus type 12‐induced chromosome aberrations are non‐random in cells from patients with Fanconi's anaemia and there is a high degree of specif