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Oxygen alkylation in the ethyl acetoacetate synthesis

✍ Scribed by G. Brieger; W.M. Pelletier

Publisher
Elsevier Science
Year
1965
Tongue
French
Weight
163 KB
Volume
6
Category
Article
ISSN
0040-4039

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✦ Synopsis

In a search for convenient preparative techniques, we have investigated the effect of solvent, halide, base, and temperature on the alkylation of the ambldent anion derived from ethyl acetoacetate. Our attention has focused on the use of dipolar aprotic solvents. A recent report (1) describing oxygen al&-lation in small yield using the standard synthesis (2) prompts us to report our findings.

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