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Oxirane as a neighboring group; synthesis of 3-oxetanol derivatives

โœ Scribed by Herman G. Richey Jr.; Donald V. Kinsman

Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
209 KB
Volume
10
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Solvolysis

reactions of esters of several 2,3 -epoxy-1 -propanols (1) have led to formation of esters of 3-oxetanols (2). 1 -0xabicyclobutonium cations (2) probably are intermediates a 2 z ki-2a

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Ten 2-aryl or heteroaryl-3-nitrosoimidazo[1,2-a]pyridine derivatives were synthesised as potential antiretroviral agents. The new compounds were characterized by elemental analysis, 1 H NMR, and by crystallography for ( 14). The compounds were devoid of any activity against HIV-1 or HIV-2.