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Synthesis of 3-Nitrosoimidazo[1,2-a]pyridine Derivatives as Potential Antiretroviral Agents

✍ Scribed by Aziz Chaouni-Benabdallah; Christophe Galtier; Hassan Allouchi; Abdelhak Kherbeche; Jean-Claude Debouzy; Jean-Claude Teulade; Olivier Chavignon; Myriam Witvrouw; Christophe Pannecouque; Jan Balzarini; Erik de Clercq; Cécile Enguehard; Alain Gueiffier

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
91 KB
Volume
334
Category
Article
ISSN
0365-6233

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✦ Synopsis

Ten 2-aryl or heteroaryl-3-nitrosoimidazo[1,2-a]pyridine derivatives were synthesised as potential antiretroviral agents. The new compounds were characterized by elemental analysis, 1 H NMR, and by crystallography for ( 14). The compounds were devoid of any activity against HIV-1 or HIV-2.

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