The alcohol 12 reacted with 4-toluenesulfonyl chloride in boiling dichloromethane solution to give the chlorinated product 13 rather than the expected tosylate 3 by a mechanism that could involve neighbouring group participation of the nitro-substituent. In contrast, the isomeric alcohol 15 reacted
Possible Neighboring Group Participation of a Nitro-Group in the Conversion of 3-Hydroxymethyl-2-(2-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline into Its 3-Chloromethyl Derivative.
β Scribed by Michael J. Donaghy; Stephen P. Stanforth
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 17 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The selective Beckmann fragmentations of multifunctionalised ketoximes have been proven to proceed effectively to give the corresponding nitriles. The chiral (__E__)β1,3,4βtriβ__O__βsubstitutedβ6βmethoxyβhexβ5βenβ2βone oxime derivatives, available from glycals and glycosyl glycals, gave
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v