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Oxidized LDL differentially regulates MMP-1 and TIMP-1 expression in vascular endothelial cells

✍ Scribed by Yan Huang; Lanxi Song; Shan Wu; Fan Fan; Maria F Lopes-Virella

Book ID
119434072
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
163 KB
Volume
156
Category
Article
ISSN
0021-9150

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## Abstract Matrix metalloproteinases (MMPs) are zinc‐dependent proteases capable of degrading extracellular matrix components. The activity of these proteases is tightly regulated through the actions of the tissue inhibitors of metalloproteinases (TIMPs). Although the regulation of MMPs and TIMPs