Differential expression of stromal MMP-1, MMP-9 and TIMP-1 in basal cell carcinomas of immunosuppressed patients and controls
✍ Scribed by Sonja Boyd; Kalle Tolvanen; Susanna Virolainen; Tiina Kuivanen; Lauri Kyllönen; Ulpu Saarialho-Kere
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 280 KB
- Volume
- 452
- Category
- Article
- ISSN
- 1432-2307
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objectives/Hypothesis: Vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) are potent mediators of tumor angiogenesis. It has been demonstrated that vestibular schwannoma VEGF expression correlates with tumor growth pattern, whereas knowledge on the expres
Enhanced expression of the type IV collagenases MMP-2 and MMP-9, or lack of their inhibitors TIMP-1 and TIMP-2, has been associated with tumour invasion and metastatic potential in several experimental models. Regulation of enzyme activity is clearly a key step in tumour invasion, and recently a pot
## Abstract Tumor progression and metastasis contribute to the great majority of breast cancer deaths. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are thought to be involved in tumor progression and metastasis. Thus, we determined whether the expression of M