Oxidative transformations in the aporphine alkaloid series
β Scribed by M.P. Cava; A. Venkateswarlu; M. Srinivasan; D.L. Edie
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- French
- Weight
- 624 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
Abstrac-Oxidation
of the non-phenolic aporphines nuciferine (1). dicentrine (3). ocopodine (4) and thalicarpine ( 7) by iodine affords the corresponding dehydroaporphines (2. 5. 6 and 8). In contrast. iodine oxidation of non-phenolic noraporphines proceeds all the way to the oxoaporphine stage: thus.
π SIMILAR VOLUMES
The isomeric imidazolopyrrolidinose 1, imidazolopiperidinose 2 and imidazoloazepanose 3, potential glycosidase inhibitors, were obtained in several steps from D-glucose.
AS the number and variety of established indole alkaloid structures increase, it becomes more and more apparent that many of the structural types derive by varying modes of cyclization of natural intermediates in which certain reactive sites have been brought to specific oxidation levels b . In such