1999 organo-silicon compounds, isocyclic C derivatives organo-silicon compounds, isocyclic C derivatives S 0064 ## 35 -194 Oxidation of α-Hydroxysilanes by Lead Tetraacetate. -Oxidation of α-hydroxysilanes with lead tetraacetate results in the formation of mixed acetyl-silyl acetals. This type of
Oxidation of α-hydroxysilanes by lead tetraacetate
✍ Scribed by María Dolores Paredes; Ricardo Alonso
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 284 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The effect of a-silyl substitution on the oxidation of alcohols by lead tetraacetate has been evaluated. Under typical conditions for converting alcohols to cyclic ethers, ct-hydroxysilanes are instead efficiently transformed into mixed acetyl-silyl acetals.
📜 SIMILAR VOLUMES
Oxidation of aliphatic ketoximes (1) and aldoximes (2) by lead tetraacetate (Pb(OAcjq) has been reported to lead to unstable geminal nitrosoacetates and to dimeric nitrosoacetates, respectively, while a,S-unsaturated and arylaldoximes afforded oxime anhydride N-oxides and carbonyl compounds (3).
IN recent years, the oxidation of monohydric alcohols to tetrohydrofuran derivatives by lead tetraacetate has been studied extensively in steroids and used successfully to functionalize the "unactivated" Cl\* or Ctp angular methyl group (1,2). We have applied this type of reaction in the bridged rin
## Lead tetmacetate oxidation of monohydric aIdloIs bearing a carbon-hydrogen bond in the 8 -position represents a valuable synthetic route to tetmhydrofurane derivatives l,2.