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Oxidation of enamines to α-hydroxy ketones and α-amino ketones using N-sulfonyloxaziridines

✍ Scribed by Franklin A. Davis; Aurelia C. Sheppard


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
235 KB
Volume
29
Category
Article
ISSN
0040-4039

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AbstractÐN-Substituted 2-aminothiazoles are synthesized in a one-pot procedure using readily available a-bromo ketones and amines. This method is compatible with a wide range of functional groups and offers a facile and ef®cient access to the class of N-thiazolyl a-amino acid derivatives.