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Oxamides as novel NR2B selective NMDA receptor antagonists

✍ Scribed by Gizella Barta-Szalai; István Borza; Éva Bozó; Csilla Kiss; Béla Ágai; Ágnes Proszenyák; György M Keserű; Anikó Gere; Sándor Kolok; Kornél Galgóczy; Csilla Horváth; Sándor Farkas; György Domány


Book ID
108073363
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
269 KB
Volume
14
Category
Article
ISSN
0960-894X

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Indole-2-carboxamides as novel NR2B sele
✍ István Borza; Sándor Kolok; Anikó Gere; Éva Ágai-Csongor; Béla Ágai; Gábor Tárká 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 136 KB

A novel series of indole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the number and position of OH groups on the indole skeleton as well as the substitution of the piperidine ring on the biological activity of the compounds was