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Indole-2-carboxamidines as novel NR2B selective NMDA receptor antagonists

✍ Scribed by István Borza; Sándor Kolok; Györgyi Ignácz-Szendrei; István Greiner; Gábor Tárkányi; Kornél Galgóczy; Csilla Horváth; Sándor Farkas; György Domány


Book ID
108073799
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
95 KB
Volume
15
Category
Article
ISSN
0960-894X

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Indole-2-carboxamides as novel NR2B sele
✍ István Borza; Sándor Kolok; Anikó Gere; Éva Ágai-Csongor; Béla Ágai; Gábor Tárká 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 136 KB

A novel series of indole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the number and position of OH groups on the indole skeleton as well as the substitution of the piperidine ring on the biological activity of the compounds was