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Overview of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic leukemia

✍ Scribed by te Raa, G. Doreen; Malcikova, Jitka; Pospisilova, Sarka; Trbusek, Martin; Mraz, Mark; Garff-Tavernier, Maria Le; Merle-Béral, Hélène; Lin, Ke; Pettitt, Andrew R.; Merkel, Olaf; Stankovic, Tatjana; van Oers, Marinus H.; Eldering, Eric; Stilgenbauer, Stephan; Zenz, Thorsten; Kater, Arnon P.

Book ID: 120307756
Publisher: Informa plc
Year: 2013
Tongue: English
Weight: 648 KB
Volume: 54
Category: Article
ISSN: 1042-8194
DOI: 10.3109/10428194.2013.796058

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## Abstract B‐cell chronic lymphocytic leukemia (B‐CLL) samples were screened for alterations in multiple tumor suppressor genes (__p53__ (17p13), __p__16 INK^4^ (9p21), and disrupted in B‐cell malignancy (__DBM__) (13q14)) by using poly‐merase chain reaction‐based assays. Eleven percent (11 of 96)