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Overproduction of the ε Subunit of DNA Polymerase III Counteracts the SOS Mutagenic Response of Escherichia coli

✍ Scribed by Piotr Jonczyk, Iwona Fijalkowska and Zygmunt Ciesla


Book ID
123636348
Publisher
National Academy of Sciences
Year
1988
Tongue
English
Weight
724 KB
Volume
85
Category
Article
ISSN
0027-8424

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The beta and beta' subunits of RNA polymerase are thought to be controlled by a translational feedback mechanism regulated by the concentration of RNA polymerase holoenzyme. To study this regulation in vivo, an inducible RNA polymerase overproduction system was developed. This system utilizes plasmi