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Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer

✍ Scribed by Yusuke Oji; Yasuo Miyoshi; Satoko Koga; Yoko Nakano; Akiko Ando; Shin-ichi Nakatsuka; Ai Ikeba; Eigo Takahashi; Nao Sakaguchi; Asumi Yokota; Naoki Hosen; Kazuhiro Ikegame; Manabu Kawakami; Akihiro Tsuboi; Yoshihiro Oka; Hiroyasu Ogawa; Katsuyuki Aozasa; Shinzaburo Noguchi; Haruo Sugiyama

Book ID
108582314
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
334 KB
Volume
94
Category
Article
ISSN
1347-9032

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Overexpression of the Wilms' tumor gene
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## Abstract Expression of the Wilms' tumor gene __WT1__ in __de novo__ lung cancer was examined using quantitative real‐time RT‐PCR and immunohistochemistry. Overexpression of the __WT1__ gene was detected by RT‐PCR in 54/56 (96%) __de novo__ non‐small cell lung cancers examined and confirmed by de

Upregulation of Wilms' tumor gene 1 (WT1
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## Abstract Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors in which β‐catenin/TCF3 mediated Wnt signaling is activated. More than 80% of desmoid tumors contain activating mutations in β‐catenin. It has been shown that the Wnt signaling pathway interacts with Wilms'