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Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma

✍ Scribed by Yusuke Oji; Hirofumi Yamamoto; Masaya Nomura; Yoko Nakano; Ai Ikeba; Shin-ichi Nakatsuka; Sakie Abeno; Eiji Kiyotoh; Tanyarat Jomgeow; Mitsugu Sekimoto; Riichiro Nezu; Yukinobu Yoshikawa; Yoshifumi Inoue; Naoki Hosen; Manabu Kawakami; Akihiro Tsuboi; Yoshihiro Oka; Hiroyasu Ogawa; Shigeo Souda; Katsuyuki Aozasa; Morito Monden; Haruo Sugiyama

Book ID
108582330
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
438 KB
Volume
94
Category
Article
ISSN
1347-9032

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Overexpression of the Wilms' tumor gene
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## Abstract Expression of the Wilms' tumor gene __WT1__ in __de novo__ lung cancer was examined using quantitative real‐time RT‐PCR and immunohistochemistry. Overexpression of the __WT1__ gene was detected by RT‐PCR in 54/56 (96%) __de novo__ non‐small cell lung cancers examined and confirmed by de

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## Abstract Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors in which β‐catenin/TCF3 mediated Wnt signaling is activated. More than 80% of desmoid tumors contain activating mutations in β‐catenin. It has been shown that the Wnt signaling pathway interacts with Wilms'