✦ LIBER ✦

Overexpression of TDP-43 causes partially p53-dependent G2/M arrest and p53-independent cell death in HeLa cells

✍ Scribed by Kikyo Lee; Hiroaki Suzuki; Sadakazu Aiso; Masaaki Matsuoka

Book ID: 116773748
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 688 KB
Volume: 506
Category: Article
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2011.11.021

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Genistein induces G2/M cell cycle arrest

Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells

✍ Yuan, Chun-Su 📂 Article 📅 2013 🏛 Spandidos Publications Ltd 🌐 English ⚖ 791 KB

Induction of p53-independent Apoptosis A

Induction of p53-independent Apoptosis Associated with G2M Arrest Following DNA Damage in Human Colon Cancer Cell Lines

✍ Arita, Daisaku ;Kambe, Mariko ;Ishioka, Chikashi ;Kanamaru, Ryunosuke 📂 Article 📅 1997 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 475 KB

Caffeine induces G2/M arrest and apoptos

Caffeine induces G2/M arrest and apoptosis via a novel p53-dependent pathway in NB4 promyelocytic leukemia cells

✍ Keisuke Ito; Tomonori Nakazato; Yoshitaka Miyakawa; Kenji Yamato; Yasuo Ikeda; M 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 342 KB 👁 1 views

## Abstract Methylxantine derivative, caffeine, is known to prevent the p53‐dependent apoptosis pathway via inhibition of ATM (ataxia telangiectasia mutated) kinase, which activates p53 by phosphorylation of the Ser‐15 residue. In contrast, it has been reported that caffeine induces p53‐mediated ap

SarCNU-induced G2/M arrest in hepatoma c

SarCNU-induced G2/M arrest in hepatoma cells is mediated by a p53-independent phosphorylation of cdc-2 at Tyr15

✍ Huynh Hung; Chow Kad Hoe Pierce; Soo Khee Chee; Panasci Lawrence; Nguyen Thanh H 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB

## Abstract Hepatocellular carcinoma (HCC) is a major health problem in the Asia‐Pacific region, with high incidence and mortality rate. There is currently no effective treatment for inoperable cases that represent the vast majority of patients. In the present study, we report that in vitro treatme

Curcumin induces G2/M cell cycle arrest

Curcumin induces G2/M cell cycle arrest in a p53-dependent manner and upregulates ING4 expression in human glioma

✍ Enyu Liu; Jing Wu; Weidong Cao; Jianning Zhang; Weiping Liu; Xiaofan Jiang; Xian 📂 Article 📅 2007 🏛 Springer US 🌐 English ⚖ 275 KB

Inactivation of p53 in normal human cell

Inactivation of p53 in normal human cells increases G2/M arrest and sensitivity to DNA-damaging agents

✍ Jocelyn Céraline; Gaël Deplanque; Brigitte Duclos; Jean-Marc Limacher; Amor Hajr 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 206 KB 👁 2 views

p53 mutations are found in about 70% of human cancers. In order to evaluate the role of these mutations in response to chemotherapeutic agents, it is important to distinguish between p53 response to DNA-damaging agents in normal and in tumour cells. Here, using normal human fibroblasts (NHFs), we sh