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Overexpression of p27kip1 induces growth arrest and apoptosis in lung cancer cell lines

✍ Scribed by Kobayashi, G; Naruse, I; Hoshino, H; Yanagitani, N; Minato, K; Takise, A; Ishihara, S.-i; Fueki, N; T, Nomoto; Saito, R


Book ID
118570218
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
109 KB
Volume
29
Category
Article
ISSN
0169-5002

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## Abstract α‐Lipoic acid is a naturally‐occurring co‐factor found in a number of multi‐enzyme complexes regulating metabolism. We report here that α‐lipoic acid induces hyperacetylation of histones in vivo and has differential effects on the growth and viability of normal versus transformed cell l