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Overexpression of p27Kip1 induces growth arrest and apoptosis in an oral cancer cell line

✍ Scribed by Supriatno; Koji Harada; Mohammad O Hoque; Takashi Bando; Hideo Yoshida; Mitsunobu Sato

Book ID: 114393887
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 201 KB
Volume: 38
Category: Article
ISSN: 1368-8375
DOI: 10.1016/s1368-8375(02)00011-8

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## Abstract α‐Lipoic acid is a naturally‐occurring co‐factor found in a number of multi‐enzyme complexes regulating metabolism. We report here that α‐lipoic acid induces hyperacetylation of histones in vivo and has differential effects on the growth and viability of normal versus transformed cell l