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Overexpression of human sperm protein 17 increases migration and decreases the chemosensitivity of human epithelial ovarian cancer cells

✍ Scribed by Fang-qiu Li; Yan-ling Han; Qun Liu; Bo Wu; Wen-bin Huang; Su-yun Zeng

Book ID: 115011690
Publisher: BioMed Central
Year: 2009
Tongue: English
Weight: 699 KB
Volume: 9
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-9-323

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## Abstract SET and MYND domain‐containing protein 3 (SMYD3) is a histone methyltransferase that plays an important role in transcriptional regulation in human carcinogenesis, and heat‐shock protein HSP90A has been shown to increase the activity of SMYD3. We previously reported that overexpression