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Osmotic regulation of the heat shock response in primary rat hepatocytes

✍ Scribed by A.K. Kurz; F. Schliess; D. Häussinger


Book ID
118568456
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
159 KB
Volume
28
Category
Article
ISSN
0168-8278

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Osmotic regulation of the heat shock res
✍ Anna Kordelia Kurz; Freimut Schliess; Prof. Dr. Dieter Häussinger 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 363 KB

The influence of cell hydration and taurine on the heat shock response was studied in primary rat hepatocytes. Heat-induced accumulation of inducible heat shock protein 70 (HSP70) mRNA and protein was increased under hypoosmotic conditions. In contrast, hyper-osmotic exposure blocked the HSP70 respo