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Heat shock inhibits the acute phase response in primary rat hepatocytes

✍ Scribed by J.E Gosnell; W.J Welch; H.W Harris


Book ID
114123642
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
181 KB
Volume
57
Category
Article
ISSN
0149-7944

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✍ Anna Kordelia Kurz; Freimut Schliess; Prof. Dr. Dieter HΓ€ussinger πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 363 KB

The influence of cell hydration and taurine on the heat shock response was studied in primary rat hepatocytes. Heat-induced accumulation of inducible heat shock protein 70 (HSP70) mRNA and protein was increased under hypoosmotic conditions. In contrast, hyper-osmotic exposure blocked the HSP70 respo