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Osmotic opening of the blood-brain barrier and local cerebral glucose utilization

✍ Scribed by Dr H. M. Pappius; H. E. Savaki; C. Fieschi; S. I. Rapoport; L. Sokoloff


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
894 KB
Volume
5
Category
Article
ISSN
0364-5134

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## Abstract The blood‐brain barrier (BBB) poses a significant impediment for the delivery of therapeutic drugs into the brain. This is particularly problematic for the treatment of malignant gliomas which are characterized by diffuse infiltration of tumor cells into normal brain where they are prot