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Original and quick access to 4-phenyl-6H-pyrrolo[1,2-a]thieno [3,2-f][1,4]diazepines

✍ Scribed by Marie Paule Foloppe; Pascal Sonnet; Sylvain Rault; Max Robba


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
95 KB
Volume
36
Category
Article
ISSN
0040-4039

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## Abstract The synthetic pathway leading to 5,6‐dihydro‐4__H__‐furo[3,2‐__f__]pyrrolo[1,2‐__a__][1,4]diazepines is described in four steps starting from α‐bromophenones __via__ 2‐amino‐3‐furonitriles.

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## Abstract Fused tricyclic 7‐phenyl‐5__H__‐thizolo[5,4‐__e__]pyrrolo[1,2‐__a__][1,4]diazepin‐10(9__H__)one (**10**) was prepared by thermolysis of 2‐phenyl‐4‐(1‐pyrrolylmethyl)thiazole‐5‐carbonyl azide (**9**) in acetic acid. In addition, starting from **10**, 7‐phenyl‐5__H__‐thiazolo [5,4‐__e__][