✦ LIBER ✦

Original and efficient method for the preparation of N-aminoamide pseudodipeptides in high optical purity

✍ Scribed by Nicolas Brosse; Arnaud Grandeury; Brigitte Jamart-Grégoire

Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 63 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)00119-3

No coin nor oath required. For personal study only.

✦ Synopsis

N-Aminoamide pseudodipeptides ZAAC[CO-N(NPht)]-AAOR can be easily obtained via the Mitsunobu protocol by using a-hydroxyesters as alcohol partners and aminoacid phthaloyl hydrazide derivatives as acidic partners. The direct conversion of the phthaloyl group into tert-butyloxycarbonyl can be performed in a three-stage one-pot protocol.

📜 SIMILAR VOLUMES

ChemInform Abstract: Original and Effici

ChemInform Abstract: Original and Efficient Method for the Preparation of N-Aminoamide Pseudodipeptides in High Optical Purity.

✍ Nicolas Brosse; Arnaud Grandeury; Brigitte Jamart-Gregoire 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

A Novel Method for the Preparation of Be

A Novel Method for the Preparation of Benzylidenecyclohexanes with High Optical Purity.

✍ Shuichi Nakamura; Takahiro Ogura; Libo Wang; Takeshi Toru 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 136 KB 👁 1 views

A highly efficient synthesis of γ-halo a

A highly efficient synthesis of γ-halo allylic alcohols and propargylic alcohols with high optical purity. Practical method for synthesis of the prostaglandin ω-chain

✍ Sentaro Okamoto; Toshiyuki Shimazaki; Yuichi Kobayashi; Fumie Sato 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 279 KB

A convenient method for the preparation

A convenient method for the preparation of mono N-alkylated cyclams and cyclens in high yields

✍ Cong Li; Wing-Tak Wong 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 78 KB

Selective and high yield synthesis of mono N-substituted derivatives of cyclam and cyclen can be achieved by using a direct and general synthetic method with very mild reaction conditions.

ChemInform Abstract: A Chemical Method f

ChemInform Abstract: A Chemical Method for the Preparation of Novel 1,5-Benzodiazepines Acting as CCK-B Antagonists in High Enantiomeric Purity.

✍ G. CUROTTO; D. DONATI; G. FINIZIA; A. URSINI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

A Chemical Method for the Preparation of Novel 1,5-Benzodiazepines Acting as CCK-B Antagonists in High Enantiomeric Purity. -Title compounds (III) are prepared from racemic precursors (I) utilizing (S)-(+)-2-(4-toluenesulfonyloxy)-phenylacetic acid methyl esters as novel reagent for the optical res

Highly Efficient Recyclable CoIII–salen

Highly Efficient Recyclable CoIII–salen Complexes in the Catalyzed Asymmetric Aminolytic Kinetic Resolution of Aryloxy/Terminal Epoxides for the Simultaneous Production of N-Protected 1,2-Amino Alcohols and the Corresponding Epoxides in High Optical Purity

✍ Rukhsana I. Kureshy; K. Jeya Prathap; Santosh Agrawal; Manish Kumar; Noor-ul H. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 697 KB