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ChemInform Abstract: A Chemical Method for the Preparation of Novel 1,5-Benzodiazepines Acting as CCK-B Antagonists in High Enantiomeric Purity.

✍ Scribed by G. CUROTTO; D. DONATI; G. FINIZIA; A. URSINI


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


A Chemical Method for the Preparation of Novel 1,5-Benzodiazepines Acting as CCK-B Antagonists in High Enantiomeric Purity.

-Title compounds (III) are prepared from racemic precursors (I) utilizing (S)-(+)-2-(4-toluenesulfonyloxy)-phenylacetic acid methyl esters as novel reagent for the optical resolution of amines. The absolute configurations of the separated enantiomers are not assigned ( some yields given in g). -(CUROTTO, G.;