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Organocatalytic Enantioselective Dipolar [3+2] Cycloadditions of Acetylenic Aldehydes with Nitrones for the Formation of Chiral 4-Isoxazolines

✍ Scribed by Xianrong Cai; Chao Wang; Jian Sun


Book ID
101424557
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
293 KB
Volume
354
Category
Article
ISSN
1615-4150

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Lanthanide triflate-catalyzed 1,3-dipola
✍ ShΕ« Kobayashi; Ryo Akiyama πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 248 KB

1,3-Dipolar cycloaddition reactions of polymer-supported nitrones with alkenes proceeded smoothly in the presence of a catalytic amount of a lanthanide triflate to afford the corresponding 2-isoxazolines in high yields. Diverse 2-isoxazoline derivatives were prepared based on these solid-phase react