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Lanthanide triflate-catalyzed 1,3-dipolar cycloaddition reactions of polymer-supported nitrones with alkenes for the preparation of diverse 2-isoxazoline derivatives

✍ Scribed by Shū Kobayashi; Ryo Akiyama


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
248 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


1,3-Dipolar cycloaddition reactions of polymer-supported nitrones with alkenes proceeded smoothly in the presence of a catalytic amount of a lanthanide triflate to afford the corresponding 2-isoxazolines in high yields. Diverse 2-isoxazoline derivatives were prepared based on these solid-phase reactions.


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