✦ LIBER ✦

Organocatalytic asymmetric 1,4-addition of organoboronic acids to γ-hydroxy α,β-unsaturated aldehyde: facile synthesis of chiral β-substituted γ-lactones

✍ Scribed by Sung-Gon Kim

Publisher: Elsevier Science
Year: 2008
Tongue: French
Weight: 179 KB
Volume: 49
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.08.025

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Organocatalytic Asy

ChemInform Abstract: Organocatalytic Asymmetric 1,4-Addition of Organoboronic Acids to γ-Hydroxy α,β-Unsaturated Aldehyde: Facile Synthesis of Chiral β-Substituted γ-Lactones.

✍ Sung-Gon Kim 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 48 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Organocatalytic Conjugate Addition of Ma

Organocatalytic Conjugate Addition of Malonates to α,β-Unsaturated Aldehydes: Asymmetric Formal Synthesis of (-)-Paroxetine, Chiral Lactams, and Lactones.

✍ Sven Brandau; Aitor Landa; Johan Franzen; Mauro Marigo; Karl Anker Joergensen 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 39 KB

Organocatalytic Conjugate Addition of Ma

Organocatalytic Conjugate Addition of Malonates to α,β-Unsaturated Aldehydes: Asymmetric Formal Synthesis of (−)-Paroxetine, Chiral Lactams, and Lactones

✍ Sven Brandau; Aitor Landa; Johan Franzén; Mauro Marigo; Karl Anker Jørgensen 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 1 views

Organocatalytic Conjugate Addition of Ma

Organocatalytic Conjugate Addition of Malonates to α,β-Unsaturated Aldehydes: Asymmetric Formal Synthesis of (−)-Paroxetine, Chiral Lactams, and Lactones

✍ Sven Brandau; Aitor Landa; Johan Franzén; Mauro Marigo; Karl Anker Jørgensen 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB 👁 1 views

Chiral lactones and lactams are endowed with a large spectrum of biological properties [1] including very important pharmaceutical activities. [2] The chiral piperidines (À)paroxetine hydrochloride 1, marketed as paxil/seroxat, and (+)-femoxetine 2 are selective serotonin reuptake inhibitors and are

ChemInform Abstract: Asymmetric Synthesi

ChemInform Abstract: Asymmetric Synthesis of γ-Hydroxy α,β-Unsaturated Aldehydes via Enantioselective Direct Addition of Propargyl Acetate to Aldehydes.

✍ Emad El-Sayed; Neel K. Anand; Erick M. Carreira 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Highly Enantioselective Organocatalytic

Highly Enantioselective Organocatalytic Michael Addition of 2-Hydroxy- 1,4-naphthoquinone to β,γ-Unsaturated α-Oxo Esters

✍ Yi-Feng Wang; Wei Zhang; Shu-Ping Luo; Guang-Cun Zhang; Ai-Bao Xia; Xiang-Sheng 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 1 views

## Abstract An organocatalytic enantioselective Michael addition of 2‐hydroxy‐1,4‐naphthoquinone to β,γ‐unsaturated α‐oxo esters has been developed. The process was promoted by bifunctional chiral amine derived squaramides according to a hydrogen‐bonding mediated activation mechanism and afforded t