The prospect of selecting oral a-ketohydroxypyrldine chelators Intended for clinical use in iron overload has been examined using several animal models of efficacy and toxicity. Studies using iron dextran-loaded mice labelled with 50Fe have shown that only the 1-substituted methyl, ethyl, (n)propyl,
β¦ LIBER β¦
Orally active chelators for the treatment of iron overload diseases
β Scribed by Alex P. Chin; Paul V. Bernhardt; Des R. Richardson
- Book ID
- 108403854
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 110 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0162-0134
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