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Oral Tolerance in Myelin Basic Protein T-Cell Receptor Transgenic Mice: Suppression of Autoimmune Encephalomyelitis and Dose-Dependent Induction of Regulatory Cells

✍ Scribed by Youhai Chen, Jun-Ichi Inobe, Vijay K. Kuchroo, Jody L. Baron, Charles A. Janeway and Howard L. Weiner


Book ID
123639446
Publisher
National Academy of Sciences
Year
1996
Tongue
English
Weight
391 KB
Volume
93
Category
Article
ISSN
0027-8424

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Early studies of murine experimental autoimmune encephalomyelitis (EAE) induced with myelin basic protein (MBP) divide various mouse strains into either "susceptible" or "resistant" phenotypes. Resistance is defined as lack of encephalitogenic responses after active immunization or adoptive transfer