Oral bioavailability and Pharmacokinetics of PAT-5A, a new insulin sensitizer in rats
โ Scribed by Rao N. V. S. Mamidi; Kasiram Katneni; Ramesh Mullangi; Rajagopalan Ramanujam
- Book ID
- 105731676
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 526 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0378-7966
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The purpose of this study was to compare the hepatic and small intestinal metabolism, and to examine bioavailability and gastroโintestinal firstโpass effects, of kaempferol in rats. Liver and small intestinal microsomes fortified with either NADPH or UDPGA were incubated with varying co
In a pharmacokinetic study, 15, 30, 60, and 150 mg kg-' intravenous and oral doses of methocarbamol were administered to rats. Differences observed in plasma clearance values, i.e. 0~0203,0~0156,0~0123, and 0-0085 1 kg-' min-' for 15,30,60, and 150 mg kg-', respectively, suggested a dosedependent ph