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OR.660. Role of Complement C4 in the Regulation of Self-Reactive B Cells

✍ Scribed by Amma Agyemang; Stefanos Tsiftsoglou; Marat Alimzhanov; Elisabeth Alicot; Thereza Imanishi-Kari; Michael Carroll


Book ID
113540602
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
44 KB
Volume
127
Category
Article
ISSN
1090-2341

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The regulation of self-reactive B cells
✍ Richard J Cornall; Christopher C Goodnow; Jason G Cyster πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 892 KB

Self-reactive B cells are eliminated in a series of checkpoints that are triggered by antigen binding. Recent reports have shown that in addition to the processes of elimination at the immature B-cell stage, B-cell anergy and regulation of T-cell help, self-reactive cells are also controlled by foll