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A critical role of complement in regulation of self-reactive B cells

โœ Scribed by Andrey P. Prodeus; Siegfried Goerg; Li-Ming Shen; Olga O. Pozdnyakova; Elisabeth M. Alicot; Christopher C. Goodnow; Michael C. Carroll


Book ID
117326244
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
335 KB
Volume
35
Category
Article
ISSN
0161-5890

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The regulation of self-reactive B cells
โœ Richard J Cornall; Christopher C Goodnow; Jason G Cyster ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 892 KB

Self-reactive B cells are eliminated in a series of checkpoints that are triggered by antigen binding. Recent reports have shown that in addition to the processes of elimination at the immature B-cell stage, B-cell anergy and regulation of T-cell help, self-reactive cells are also controlled by foll