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OR.106. Single-cell Analysis Reveals Non-suppressive CD4+FOXP3+Regulatory T Cells in Human Peripheral Blood

✍ Scribed by Eva d'Hennezel

Book ID
113540879
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
36 KB
Volume
131
Category
Article
ISSN
1090-2341

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The transcription factor FOXP3 plays a key role in CD4 + CD25 + regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4 + CD25 + cells that express FOXP3 protein