CD4+CD25+FOXP3+ regulatory T cells from human thymus and cord blood suppress antigen-specific T cell responses
✍ Scribed by Kajsa Wing; Pia Larsson; Kerstin Sandström; Samuel B. Lundin; Elisabeth Suri-Payer; Anna Rudin
- Book ID
- 108781708
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 356 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0019-2805
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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a
## Abstract ## Background The purpose of this study was to investigate the presence of CD4^+^CD25^+^FOXP3^+^ regulatory T (Treg) cells both in peripheral blood and local tumors in patients with nasal inverted papilloma (NIP). ## Methods By using flow cytometry, the frequencies of CD4^+^CD25^+^FO