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OR02-4 DNAzyme AND ANTIGENE STRATEGIES TO INHIBIT THE INSULIN-LIKE GROWTH FACTOR I GENE EXPRESSION IN TUMOR MODELS

โœ Scribed by Jean-Christophe Francois; Alesya Fokina; Kahina Oussedik; Mariya Meschaninova; Paola Arimondo; Alya Venyaminova


Book ID
117734386
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
79 KB
Volume
16
Category
Article
ISSN
1096-6374

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Mutations in the WTI tumor suppressor gene are known t o contribute t o the development of Wilms' tumor (WT) and associated gonadal abnormalities. WTI is expressed principally in the fetal kidney, developing gonads, and spleen and also in the mesothelium, which lines the coelomic cavities. These tis