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Tumor Necrosis Factor-α and Basic Fibroblast Growth Factor Differentially Inhibit the Insulin-like Growth Factor-I Induced Expression of Myogenin in C2C12 Myoblasts

✍ Scribed by Matthew D. Layne; Stephen R. Farmer

Book ID
115603282
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
286 KB
Volume
249
Category
Article
ISSN
0014-4827

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Insulin-like growth factors (IGF-I and I
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✍ Emily J. Foulstone; Kate A. Meadows; Jeff M.P. Holly; Claire E.H. Stewart 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB

## Abstract IGF‐I and IGF‐II are thought to be unique in their ability to promote muscle cell differentiation. Murine C2 myoblasts differentiate when placed into low serum media (LSM), accompanied by increased IGF‐II and IGF binding protein‐5 (IGFBP‐5) production. Addition of 20 ng/ml TNFα on trans