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Optimized labeling of NOTA-conjugated octreotide with F-18

✍ Scribed by Peter Laverman; Christopher A. D’Souza; Annemarie Eek; William J. McBride; Robert M. Sharkey; Wim J. G. Oyen; David M. Goldenberg; Otto C. Boerman


Book ID
107694008
Publisher
S. Karger AG
Year
2011
Tongue
English
Weight
319 KB
Volume
33
Category
Article
ISSN
1010-4283

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## Abstract We have labeled proinsulin connecting peptide (C‐peptide) with fluorine‐18 (__t__~½~=109.7 min) in order to perform __in vivo__ biodistribution and pharmacokinetic studies with position emission tomography (PET). This study reports the optimization of the conjugation labeling in the N‐t