SUI(IvLRY ## Ritanserin has been labelled with 18F to visualize the serotoninergic receptors by Positron Emission Tomography (PET). The synthesis was carried out by a nucleophilic substitution of a nitro substituent of a ni trophenylketone by 18F-and then addition of a Grignard reagent to the ket
Labeling of a serotoninergic ligand with 18F : [18F] setoperone
β Scribed by C. Crouzel; M. Venet; T. Irie; G. Sanz; C. Boullais
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- French
- Weight
- 363 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract An efficient preparation of __N__βsuccinimidyl 4β[^18^F]fluorobenzoate ([^18^F]SFB) based on a convenient threeβstep, oneβpot procedure is described. [^18^F]Fluorination of the precursor ethyl 4β(trimethylammonium triflate)benzoate gave ethyl 4β[^18^F]fluorobenzoate. Saponification of t
The Suzuki reaction of organoboron compounds with 4-[ 18 F]fluoroiodobenzene has been developed as a novel radiolabelling technique in 18 F chemistry. The crosscoupling reaction of p-tolylboronic acid with 4-[ 18 F]fluoroiodobenzene was used to screen different palladium complexes, bases and solvent
Fluorination with 18F-F2 and 18F-AcOF were compared for the synthesis of 18F-fluorophenylalanines. L-phenylalanine in CF,COOH trapped 18F-AcOF more effectively than 18F-F2. The main product was ortho-18F-fluorophenylalanine when 18F-AcOF was used as a reagent. Lower radiochemical yield of 18F-fluoro