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Optimization of the Chiral Inversion of 2-Phenylpropionic Acid by Verticillium lecanii

โœ Scribed by MICHAEL J. THOMASON; WILLIAM RHYS-WILLIAMS; ANDREW W. LLOYD; GEOFFREY W. HANLON


Book ID
118110653
Publisher
Pharmaceutical Press
Year
1997
Tongue
English
Weight
716 KB
Volume
49
Category
Article
ISSN
2042-7158

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โœ M. J. Thomason; W. Rhys-Williams; Y.-F. Hung; J. A. Baker; G. W. Hanlon; A. W. L ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 182 KB

Previous investigations have described the development of nongrowing suspensions of Verticillium lecanii as a microbial model of the mammalian chiral inversion of the 2-arylpropionic acids (2-APAs). Mechanistic studies in mammals have shown that inversion involves loss of the โฃ-methine proton but re