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Demonstration of the chiral inversion of ibuprofen by Verticillium lecanii in non-growing cultures

✍ Scribed by M.J. Thomason; W. Rhys-Williams; A.J. Hutt; A.W. Lloyd; G.W. Hanlon

Book ID
111190280
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
318 KB
Volume
23
Category
Article
ISSN
0266-8254

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✍ M. J. Thomason; W. Rhys-Williams; Y.-F. Hung; J. A. Baker; G. W. Hanlon; A. W. L πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 182 KB

Previous investigations have described the development of nongrowing suspensions of Verticillium lecanii as a microbial model of the mammalian chiral inversion of the 2-arylpropionic acids (2-APAs). Mechanistic studies in mammals have shown that inversion involves loss of the ␣-methine proton but re